Indian Journal of Advances in Chemical Science, Volume: 10, Issue : 4, December 2022

 
             
   
   

ISSN No.: 2320-0898 (Print); 2320-0928 (Electronic)

 

DOI: 10.22607/IJACS.2022.1004008

   

Review Article

     

Synthesis of Heterosteroids and their Biological Evaluation: A Review

   

Ayaz Mahmood Dar*

 

ABSTRACT

 

Steroids are the compounds of prime importance due to being the fundamental class of biologically signaling molecules. Their profound biological activities are well validated. They can regulate a variety of biological processes and, thus, have the potential to act as drugs for the treatment of a number of diseases including breast cancer, prostate cancer, oxidation problems, and microbial infections. The diversity in the biological action might be due to the presence of different functional groups located around the tetracyclic core which serves as substrates for different targets. The advantage of employing hydrophobic steroid units is their ability to interact with cell membranes and thus pave the way for biological activity of such hybrid molecules. This review depicts not only the synthesis of different heterosteroids but also their biological behavior such as anticancer, antioxidant,
antibacterial, and antifungal activity.

 

 

 

     

Key words: Heterosteroid, Breast cancer, Prostate cancer, Antioxidant and antimicrobial.

 

 

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