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In the present work, we have synthesized
nitro, phenyl, nitrophenyl, and methyl phenylhydrazone derivatives
of alizarin and compared their antioxidant activity. The antioxidant
activities of each derivative were compared using electrochemical
assay with glassy carbon electrodes. The X-ray diffraction studies
of compounds revealed that prominent peaks at 43 2q and 49 2q
confirm the formation alizarin, whereas the intensity varies
accordingly with the functional groups attached to it. This was
further confirmed by H1 nuclear magnetic resonance. The antioxidant
activities were interpreted by cyclic voltammetry that depends on
the parameters such as anodic peak current, anodic peak potential,
and area swept by the curve. The maximum antioxidant activity was
observed in phenylhydrazone derivative of alizarin. The area of the
peak and peak potential was observed at 108.017 μc and 347.498 mv,
respectively. Hence, the synthesis of the above derivatives of
alizarin clearly explains the influence of functional groups on
antioxidant activity. |
