Ambient Ionization Mass Spectrometry in Biomedical Research: An Overview

 
             
   
   

DOI: 10.22607/IJACS.2023.1103002

   

Review Article

     

 

   
Bharath Kumar*

ABSTRACT

 

Analytical chemistry has undergone a revolution thanks to ambient ionization mass spectrometry (AIMS), which makes it possible-to analyze samples quickly and directly in their natural state. The analytical community has led the continued development of-AIMS since its inception almost 20 years ago, spurred on by the plethora of benefits it offers in addition to conventional mass-spectrometry (MS). Since the development of desorption electrospray ionization MS, ambient MS techniques have become-more popular in a range of disciplines, including food science and health. Because it requires little sample preparation andoffers quick, direct analysis of samples in a range of physical states, AIMS is gaining popularity in the domain of metabolomics.Consequently, attention in AIMS has rapidly grown among analytical communities around the world, and AIMS methodologies
are becoming more and more ingrained in regular laboraprocedures. This annual review describes the use of AIMS in2022 with an emphasis on biomedical applications. Even though some new methods are being developed, AIMS research is-increasingly committed to improving the methods that already exist, particularly in terms of repeatability, quantification, andfunctionality.

 

 

 

     

Key words: Ambient ionization, Atmospheric ionization, Desorption ionization, Mass spectrometry imaging

 

 

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Indian Journal of Advances in Chemical Science,

Volume: 11, Issue : 3, August 2023

ISSN No.: 2320-0898 (Print); 2320-0928 (Electronic)

   
     
                 
     
                 
                 
                 
               
 

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