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Indian Journal of Advances in Chemical Science Volume: 5,
Issue: 2, April 2017 |
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ISSN No.: 2320-0898 (Print);
2320-0928 (Electronic)
DOI:
10.22607/IJACS.2017.502005
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Research Article
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Fabrication of Gold
Nanoparticles from Prosopis juliflora Leaves Extract by Green
Method for Potential Antibacterial Application |
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K. S. V. Krishna Rao*,
P. Rama Subba Reddy, E. Chandra Sekhar |
ABSTRACT |
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Incorporation of green chemistry
principles to nanotechnology is one of the key concerns in
nanoscience research. There is growing need to develop
environmentally benign metal nanoparticle fabrication progression
that does not use toxic chemicals in the synthetic conventions to
avoid antagonistic effects in medical applications. In this process
using rapid, convenient and environment-friendly method for the
fabrication of gold nanoparticles (Prosopis juliflora [PJ]-GNPs)
by reducing aurum chloride with the aqueous extract of PJ leaves. To
elevate the process parameters involved in the fabrication of PJ-GNPs
by green method including extract concentration Au+3 ion
concentration and time intervals. The antibacterial activity is
carried out by disc diffusion method. The green synthesized PJ-GNPs
are primarily confirmed by visual observations through color
changing of the reaction mixture from light yellow to ruby red. The
surface plasmon resonance of PJ-GNPs is obtained at 520 nm, and the
effect of the phytochemicals present in PJ extract, including
phenolic compounds, phytosterols, and quinones on formation of
stable PJ-GNPs are investigated by ultraviolet-visible spectroscopy,
Fourier transform infrared spectroscopy; the size of PJ-GNPs is
confirmed by dynamic light scattering and transmission electron
microscopy. The morphology and shape of the PJ-GNPs are determined
by scanning electron microscopy and energy dispersive X-ray
analysis. The antibacterial activity of PJ-GNPs is studied against
pathogenic microbial strains.. |
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Key words: Biosynthesis, Green
method, Prosopis juliflora, Gold nanoparticles, Antibacterial
activity. |
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Copyright © 2012
KROS Publications |
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