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Indian Journal of Advances in Chemical Science Volume: 6,
Issue 2: , April 2018 |
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ISSN No.: 2320-0898 (Print);
2320-0928 (Electronic)
DOI:
10.22607/IJACS.2018.602001
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Research Article
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Gout Pain Caused by Uric Acid
Molecule and Its Solution Caused by Citric Acid Molecule: A
Physicochemical Investigation |
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Mahendra Nath Roy*,
Subhankar Choudhury, Deepak Ekka, Raja Ghosh
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ABSTRACT |
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The effect of relief from gout pain
due to the restriction of precipitation of uric acid (UA) by citric
acid (CA) has been studied through physicochemical study. Here, we
have carried out the density (ρ) and viscosity (η) measurements of
CA in w1=0.00001, 0.00002, and 0.00003 mass fraction of aqueous UA
binary mixtures at T=298.15K, 303.15K, 308.15K, and 313.15K and at
pressure 1.013 bar. These measurements have been performed to
ternary mixture (CA + UA + water) to derive some important
parameters, namely, limiting apparent molar volume (φV0),
viscosity B-coefficients from extended Masson equation, and
Jones–Dole equation, respectively. The refractive index (nD)
has been done on the same ternary mixtures at T=298.15K.
Lorentz–Lorenz equation has used to evaluate molar refractive index
(RM) and limiting molar index (RM0).
These parameters have been interpreted in terms of interactions of
solute itself and with solvent. |
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Key words: Apparent
molar volume, Citric acid, Molar refraction, Solute-solvent
interactions, Uric acid, Viscosity B-coefficient |
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[Download Full Article
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KROS Publications |
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